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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1d448505a833ff2f54f4c3b6424958d537cc7a72556f8bce9497ec99982144' 
  AND token = 'p900/Q3LIZseZQQuMz40veQ0MODqQdDpV+4rUsUGYHQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}