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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2aff78ce8fe79056b76093e3ba9340fb31ea7e87640327020d0c41ded0a8952' 
  AND token = 'EPWiXJThYwr/lENObeGyfq7nYFR631yFoEW1jooNKpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}