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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2e8b01fab95acdbbae0febe84f397fc187c6c37d14acccc29336a1c7a5a3ba' 
  AND token = 'mt9iDZNHqcY/s3hp+c/BLTvghzbusXddCiPVPa+xVuk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}