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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e91ac204fb5412e4f4e2a40faff747af4244002f7f0990e1469d56dc074c2d01' 
  AND token = 'LQ5zV+wwpRWEtTzFseKogkM6owO+TqZT7UT/ZO1ZfZs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}