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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1e40d54295e565717a612b4446cf147853a5447e6515383cc5fc3e0076eb3a3' 
  AND token = 'k3Z5bD+lyjYANlN851MgPqxHM71stjoWdyncfuPIFTs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}