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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e8a290cdfa833a8b3224cc323e0f3880f7c211b814e5f3c06fe1f441cc8b94f' 
  AND token = '3HYmnrencxaPoVfETiT1dmvczfWuOpd6pxrWan5omxw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}