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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd43541ab0e37f7d431fcc84c5f229c8ebfdd7007abb1dfac00166867e29dba03' 
  AND token = 'sy28OyQOMc/dDhVudUl9se7LtjJzMY4lHTB7icN5NFc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}