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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e84492f8c1fed9383b422884f498c682a9fa8fd71924d65e0876e204633cbdef' 
  AND token = '+liefszXrVyu9I20WU/oVJfY3t2eSvWfMDNW/pWvyls=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}