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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f8e5847ed34cf51d967ea569b4a37c8b197fb6ce3a7c35b916c9ae071c4daeb8' 
  AND token = 'kmo4rYDqPoD0XAMesPIK8W1UQgE6wtmJ2RVEhWLExc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}