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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0449812c1e23257b3f8f37ecc55ed4af6067babc2bacdd2c59b84199daee6e4' 
  AND token = 'PxV4+Wwt8+u2ZzMtow8PpsFV/Wk0MkoIDs6sip3tCg8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}