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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ba9fb9bb7f392c029a10308fef60295de0df7a1a7829669ccc80ab055b7f6c6' 
  AND token = 'UMRTWK4XlyvYGDBfh65Pw18krcNczKRG67CHS/dSJ6k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}