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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a2c1d6b55162a2be23df868222f6397989edd0a4d6183d9edf05a6e3cdd74b52' 
  AND token = 'plIAGxTK2HInH/4A2tMTKuc3L0jZ71roMKkorG2R9ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}