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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2112ab29c5f90849117fbc5d08a73a87daef1616182e530db5ec4c7b753f2185' 
  AND token = '3vXYpQ7R2F+xTB0UTOCDJh65wQaDkJmhkowGdHG429k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}