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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147fe98e769e65cd9c1fa3b0ba709a9027f0182de15a5f2a9120407f779fa373' 
  AND token = 'WmTxsEFqYbeVyiOItU05jUj6pMUjtn9OsxP02e8Ay9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}