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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29629354f3133b74509fc05352c3f4af07b0f17877806c8443e524b92be1911' 
  AND token = 'Lvbs1cxGPH9LcJtTr9U1luU8+uieVIOqIAG/0QMHIoU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}