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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e25d23968309e5dab647422dbc8eb4144ec050c5cf3a3ba229b45b4b69f584d' 
  AND token = 'podndX7XCPni2jStdFy8GUXJeygaVys+r1DySKzdL2k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}