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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50f4be4cf44b2695141ebcd6fb4e64c10d6990bdc148801ae1c96512873260dc' 
  AND token = 'pOJ8Hk/tw4LIw7EKP4nGYa3P90ooEbVG0TpiWnC4kdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}