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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50b4bfc1d47658e42202761787269f0e2efc6e96810989c458a3eb9e9466e3d8' 
  AND token = 'RPVJ5Sig+CCa2wHYeOU/lChceQF/ixBmBAN6wjl0e1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}