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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a988d307a121018cc55c065173f998f0dee65d491a130e37772b91debefc4bd' 
  AND token = 'P7IfVkgV+NtiV6gddbX2I+Ggv2KMVXCAIkLaW9d/uFs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}