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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd324c6fc57418049bcde1cc148c7a50391f84c73d99f28eb06ab8941d35dec23' 
  AND token = 'P5jRyuyVix6/8Z8k5MHCpfUWIkc5gkkh7C9/nGfBu9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}