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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '147e351949df4a0027319aae0a302ee3cedae9a3e6084bb17971f79e55a8c60b' 
  AND token = 'QKuZGEEZtU6A4s+wCGJ0USX5T2YqiLCi3Y7Zvz/Wbl0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}