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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7f8be5f673eb730b6ebaa578331fdb3853a3ef42bedd285e1e158a6df8fdcce' 
  AND token = '28qlvjJ/BXbaFqXAAXRkiqqiWcvnVFMgWqQJVt4wFUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}