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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '855a05d3df356918290de6ea99acf37c45d09a87ce1018a13e2eede35856db40' 
  AND token = 'w8XxqXuW5mJCgVJZC7YA8YOQq3wdbM3xgM/4YNJlD0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}