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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ad3e8349095592408898c7f2c988546787e28b4542b30d3d60e556d7be32062' 
  AND token = 'WF3sI2xpCOyzNMmQvVl+hX1Qg0yLcBaK6ntFkOwsdig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}