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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c6b7e99b71c6014f74d7058f7fb5a3d151906c5b12af3a214edc43a31c5fbec' 
  AND token = 'gu53/ooDKLZrdEwNrH/KtAntwzC87dEh8WuZEeedaVo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}