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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc2ab556b7757f1c774ff1b3d824439f9f57bcb3922283ad225edd133c642b70' 
  AND token = 'yxRQSTn8MCTh5NYRlEQBtY1Nwf8RzjCXRLM2E2TFRs4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}