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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4cd309d526f0c2be5d1629d22083342594ab992da5da187b6fc2118dc2e1e2b' 
  AND token = 'PesaKuPwLm2pbCyRFSSVI4okAcN31G2sN+TpXLIuskw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}