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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c16816c54dbc089e978ed0de487102b2ec791658df69a20a74684102bfad25de' 
  AND token = 'hCx4LUK09+uy4l5Thwj2r7C2+5FMUPEYWDsci3DmSpQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}