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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e3196cded4798e02b16c15e01b06a0a55d752555c54442189198a08113b7a5b2' 
  AND token = 'H7N8Xx/SiK+ytDVhPKodUcDCY3V5mSSKjJC4QWPjc7g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}