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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb808dd359ea8de69d675bab78f8090dbdb4250f7304e16d20fdfa32a83a59f' 
  AND token = 'l897rIOJsCHCcju35891/4chjeIfSsLtAmYvT2jKei0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}