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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '519ea715c02925899ce644f7a2304bf0ecfa48348046794364d26f23802a1b40' 
  AND token = '6XMVP30tt2vIHTRIJn3/QsibK44wsv7CifPD8XCcV08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}