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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad17e05d955f56b3896d069aad2901664407f1c9824ec67d5b9ea4b23dc0f1bd' 
  AND token = 'zEa+8qqYRV1UeiUhbNOdHbrYJdak7uqmb3FE+2RU8rE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}