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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1add9a713df222f54a29164a85cb07d45a8919e78aadc9db31a9d7abefc221a9' 
  AND token = 'SiAff1qTR1k1e9dOv0vZxVYoUR+k3AEZMrVHcb9EAKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}