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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de952bf1ebec36ca776bc48efdac06b0872b407c596bb449ad21ab0b3fafde2f' 
  AND token = 'PwnC1jswG2+SWJCftt2YiDnfaQ/FjRBBRfmD3U3Rlq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}