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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c80e6c91d68132e3c19bfef347e111e1e0a998b3d3413a5420f09fb25153601a' 
  AND token = '8cbU9BTIfLU7NoB/rryToEOBDc5tQ9G3xM8+zeOe27U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}