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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e16353306a05f82fbcd5706d87b0701b57a04a61fbfbddc87271f186fa00ef7' 
  AND token = '23M/FuWFZ2dpOf0+aMRVQEg6796q/AFcPIjvxHoj8Is=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}