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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b14ee33109e959d543f32b76ac31c6eded4fa53cff326ed93c0aee5d45858b39' 
  AND token = 'S/XCeQrHMy17kCKXox52ab/nrTG6ipxdzO6Uqp5Pg5E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}