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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd166c59d86de38e1a1bcda9b78d91333acd649b4f20f902e849c73a05c2d8f8d' 
  AND token = '9ECm1YTd44phMkcNADGNaX8lDB95XVethDIwIvOyp+I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}