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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2bf77d58126cada3a3208c229f285efaf41b76eeb726ed6341e111cd73753b2c' 
  AND token = 'x5g5jAmS2+BECUUL72IlWRtUaDHNM7qvXQ+m+uxkXLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}