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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0da181db4d69f52b205f072cbfd299c2b565c0ee7979c77863290117dc28f8bf' 
  AND token = '5XcY9xrM0X6MJJzUpg0k4SchJAgGuEEFPhTd3nv9iYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}