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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09c06f289fc8990c778ed9200d212a873fa546a5d8cf867adf3b06a725b5f44b' 
  AND token = '163vmUUTbFu+lVuUs70082uCRXdHMMPTWhXvay6u9qk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}