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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '858be576fab481d58ffa743be1082df166a3b0bb07f8a722b2a9600e56c3d455' 
  AND token = 'zL79EndV76aiEnSA+sJNFtO3EGViiud34V+cVI1srzA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}