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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2d9690edc362ea44e5c125b0f4fe1872e97c78d72397e2e2b17e453954901b2' 
  AND token = '9JekG+GixbDgeNj6djOXKh8egiFVyyDcqoOZSM2+2vo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}