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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48e7e67ea4663acf98d7e90f6e4bec9f50cf3ad23c7c7ae961975b71e0cccab5' 
  AND token = 'VftJUDsL/lDSuGZsVnS3fkc7DUijrfUSOW8df4EK1zo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}