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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8b7a2ea74d04577ad656cff46c2718ccf706d516463eb9f56a03b772eb2e590' 
  AND token = 'HNwznb5oOG8em7PY/lZCwekGR4EXpmfR1TQ1PFvZpik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}