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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ca545aec177cc08a1db9638472c0b5ff3b25e0e864b81e91f064bd569b3884f' 
  AND token = '74xoQn9a2AbP2AP/t+gPzXYrZ0CukA3+9lp/3CRR/rY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}