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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b82560ddd5ae366d8b18eba95909a57f820d7e0cb4229586f16f7fee79daaa' 
  AND token = 'Eb9OqQHS0JUZpU7fJkMpgh61i/SaWP5OOkyBEgccFgk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}