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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '805a6f46d42007d42c7f0068241c241ab8b3e0f9b1a60283b63028eacc7aa265' 
  AND token = 'NrNsd9fp+Th7r6Ycg3PasAZR2AbEeyTvsSUsucH7JiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}