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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'edd800d62ca17bf085c5926bb40f03cbdf78481d2d3e96f4a66e2808aa53e397' 
  AND token = 's7GFqwp+bv7z6fnf/iAN8rE4skf93FcYZRQ03+73xcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}