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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66b535a4206e151ad9f747c9ac978012e42cdc03fe3f573c0278148cde9c15c' 
  AND token = 'xdrwQjpMmKaY8O4iTAW/8TsnvzSP7fRWq3aNClW7kio=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}